Basic Information
VIS ID
TVIS10016526
Fusion event
HBV-LOC101928849 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
406
End
441
Orient
+
Integrated sequence
TCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGG
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
121728336/118966058 (Hg38)
End
121728371/118966093 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101928849
Nearest miRNA
hsa-let-7a-1/Upstream/4756529; hsa-mir-12126/Downstream/1278886;
Nearest TSS
ENST00000422679/Upstream/225495; ENST00000565320/Downstream/242793;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1220694, chr9-CpG: 97/Downstream/402715
Upstream sequence
AAGCTATGACCTTTTTCCCACGATGGCTTCTCTCCTTGTCACTAAAAGCTGGAGACTCTTTATGTCTGAAGGACATGTTTGAGCACAGCAGCATTTGAAA
Downstream sequence
GAGGTGCCATCCTATTAAAAGTAGTTAATAGTTTTTAAATTTATGTCCCgtgtcagtattgttctaagtactatacatgtacaatggtatttaattctta
Target sequence
AGCAAATATGTAGTCACATAAAGTATACTCTATTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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