Basic Information
VIS ID
TVIS10016531
Fusion event
HBV-LOC107985692 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1398
End
1433
Orient
+
Integrated sequence
ACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCC
Host Sequence
Chromosome
chrX
Cytoband
q24
Reference genome
GRCh37/hg19
Start
118397330/119263367 (Hg38)
End
118397365/119263402 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107985692
Nearest miRNA
hsa-let-7f-2/Upstream/876896; hsa-mir-105-1/Downstream/383336;
Nearest TSS
ENST00000429181/Upstream/27114; ENST00000428222/Downstream/28127;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/26357, chrX-CpG: 66/Downstream/9576
Upstream sequence
ATCGCTATTGCACTCAGTCTCCATCCCTActgtctctgtctctgtccctgtctctgtcttcctctctctctctctctctgtctgtctgtctctCCCCTTG
Downstream sequence
ctgcaatcaaggtagtcaaaatacccattgtccctccacatttcctCCCTACCCTCATCAATCACTGATCTAGCTGCAAAATAttttgttttgagacagg
Target sequence
ttttgacatatgtatacacacctatgaaactatca
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate