Basic Information
VIS ID
TVIS10016532
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
626
End
661
Orient
+
Integrated sequence
TTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCG
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh37/hg19
Start
122289875/123156022 (Hg38)
End
122289910/123156057 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7f-2/Upstream/1784969; hsa-mir-105-1/Downstream/11013321;
Nearest TSS
ENST00000429181/Upstream/1284153; ENST00000616590/Downstream/28096;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2107906, chrX-CpG: 29/Downstream/28843
Nearby gene
GLUD2(-2106114) ; GRIA3(+28185) ;
Upstream sequence
ACTTCATAGATCTCCTCTGGGTAGCATGTATTTggattgtggagccagattgcctggatttgaagcatagtgctgccgtttcttagccatgtgtgagctt
Downstream sequence
CACAAAATAGTGCAGCAGTGTCATAATCACAGCCTAAAGAATTCAATTGCCTTTTGTTATCAAGAGTAACAATGGCTTTAGTATTTAGGAAACATTTTGA
Target sequence
TTGGAAAGCTTTTGCCCTAATTGCTCTTGAGCAGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate