Basic Information
VIS ID
TVIS10016533
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3104
End
3139
Orient
+
Integrated sequence
ACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTG
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh37/hg19
Start
125663323/126529340 (Hg38)
End
125663358/126529375 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7f-2/Upstream/5158287; hsa-mir-105-1/Downstream/7640003;
Nearest TSS
ENST00000429181/Upstream/363243; ENST00000371125/Downstream/23476;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/362887, chrX-CpG: 109/Downstream/22353
Upstream sequence
tctagttgtctcaaaaaagtcatttgtatattatacattaaatcagaatccaaacaaggtgcatacactgtatttggttgatatgcttctctcatatctc
Downstream sequence
CAGAAGTAGAAGTGTTTATAGATAGATTGAATTAGCCTCAGGTAATAAAAAATGTATTTTCAGTGGTAAATCTACTTTCATCTATGGATGATGCCTTTTG
Target sequence
TTATAGTAAATGGCTCTTTCATATTTTAATTATGT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate