VISDB Viral Integration Site DataBase

VIS ID

TVIS10016540

Fusion event

HBV-EIF4B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1706

Orient

-

Integrated sequence

ACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGT| |CCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCA

Chromosome

chr12

Cytoband

q13.13

Reference genome

Start

End

53410558/53016774 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-16-5p ; hsa-mir-23b-5p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/117790; hsa-let-7i/Downstream/40170;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/9662, chr12-CpG: 106/Downstream/30021

Nearby gene

KRT18(-63873) ; LOC283335(+26414) ;

Upstream sequence

AGGCCCTGATTCGTTGTCCCTACCTGGCTGTATCTCTGTCTTTCCCAAAGTTAGGTTCATCATCTGACTTTGCAAATACATTTTCCTTTTTTTTCTTTAT

Downstream sequence

ATTTAGTTTACTGAAGAGAAAAATATGCTCACTAAATTCATCACCCACCATCATGAGATAAACCCAAGAAAATAATCCCTGAACTAAAACCCAAAACAAG