VISDB Viral Integration Site DataBase

VIS ID

TVIS10016541

Fusion event

HBV-TMEM132C integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2437

Orient

+

Integrated sequence

TTTTGTTAGGGTTTAAATGTATACCCAAAGACAAAAGAAAATTGGTAACAGCGGTAAAAAGGGACTCAAGATGCTGTACAGACTTGGCCCCCAATACCAC| |ATCATCCATATAACTGAAAGCCAAACAGTGGGGGAAAGCCCTACGAACCACTGAACAAATGGCACTAGTAAACTGAGCCAGGAGAAACGGGCTGAGGCCC

Chromosome

chr12

Cytoband

q24.32

Reference genome

Start

End

128866413/128381868 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-7156-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-1184 ; hsa-mir-1976 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-4742-5p ; hsa-mir-141-5p

Nearest miRNA

hsa-let-7i/Upstream/87690; hsa-mir-6763/Downstream/4200129;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/15658, chr12-CpG: 19/Downstream/33400

Nearby gene

MIR3612(-87690) ; SLC15A4(+411325) ;

Upstream sequence

agcaagcaaattcaaagaagtctgttgtgcaaccatagcctttgcagtagaatctgctatacagcctattatgagggatcaatttctttctttcttcttt

Downstream sequence

aagaataaatgtttttcacaatatgttaaaatgtcagagaaaaagaaaattgcaaagattttgtaatttactataggaactcaacctaatcttaatcaaa