Basic Information
VIS ID
TVIS10016543
Fusion event
HBV-LINC00871 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1797
Orient
-
Integrated sequence
CGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCAC| |AGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGC
Host Sequence
Chromosome
chr14
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
46917414/46448211 (Hg38)
End
46917414/46448211 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC00871
Nearest miRNA
hsa-mir-208a/Upstream/9495820; hsa-mir-1185-1/Downstream/1312784;
Nearest TSS
ENST00000550708/Upstream/384052; ENST00000556071/Downstream/23148;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1194612, chr14-CpG: 30/Downstream/203454
Nearby gene
MIS18BP1(-1194809) ; RPL10L(+202805) ;
Upstream sequence
gcatggtggcaagcacctgtaatcacagctacttgggagggtgaggcatgagacttgctcggacccaggaggaggaggttgcagcgagccgagattgtgc
Downstream sequence
agaataaagttttatgtaattgtgggagagactggggaaaaaaaaatctaagggagatttgggagatcagggaaaagtcacaaatcagtcctactaaaat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate