Basic Information
VIS ID
TVIS10016545
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1706
Orient
-
Integrated sequence
ACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGT| |CCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCA
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
59229800/59195896 (Hg38)
End
59229800/59195896 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1225/Upstream/1423544; hsa-mir-11401/Downstream/8006425;
Nearest TSS
ENST00000527434/Upstream/315683; ENST00000568279/Downstream/659457;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/461472, chr16-CpG: 19/Downstream/558992
Nearby gene
GOT2(-461554) ; APOOP5(+558244) ;
Upstream sequence
ggctgatcttgacctcctgatctcaggtgatctgcccatcttggcctcccaaagtgctgagatgacaagcgtgtgccaccacgcccagcctgcaaagttc
Downstream sequence
TGGCACGGTACCTGGAAAAGGGTAGGCTCCACAAACGTGTTCACTGCATAAATAAGAGGTGGGAGAAGGCAGCCTTTGTCTGGAAATTCACAtctcagtt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate