VISDB Viral Integration Site DataBase

VIS ID

TVIS10016546

Fusion event

HBV-RPH3AL integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1781

Orient

-

Integrated sequence

CAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGG| |ATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGC

Chromosome

chr17

Cytoband

p13.3

Reference genome

Start

End

232069/382278 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-16-5p ; hsa-mir-3144-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-3649 ; hsa-mir-492 ; hsa-mir-6746-5p ; hsa-mir-4704-3p ; hsa-mir-544b ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-1911-3p ; hsa-mir-1304-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-500a-3p ; hsa-mir-6765-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6804-3p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-1827 ; hsa-mir-3192-5p ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3680-5p ; hsa-mir-4798-3p ; hsa-mir-7851-3p ; hsa-mir-34b-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-5572 ; hsa-mir-3942-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-5100 ; hsa-mir-7704 ; hsa-mir-615-5p ; hsa-mir-6793-3p ; hsa-mir-1288-5p ; hsa-mir-1273e ; hsa-mir-219b-3p ; hsa-mir-25-5p ; hsa-mir-302f ; hsa-mir-423-3p ; hsa-mir-4329 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4695-5p ; hsa-mir-6087 ; hsa-mir-658 ; hsa-mir-6771-5p ; hsa-mir-6840-3p

Nearest miRNA

hsa-mir-10226/Downstream/640198;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/25402, chr17-CpG: 137/Downstream/2910

Nearby gene

RPH3AL(-29436) ; C17orf97(+28048) ;

Upstream sequence

AGGAGTGCAAAAGGTTTATTGAAAAAAACAAAAACAAACTAAAATCTGTtttgaagcctgcaggacattagagggtgatgtccaatagatagagatgcac

Downstream sequence

CTTTCTCAACACCCCTGCAGTACCCTGCTCTGGGCGTCCCCTGCCCGGATATCTGTGAGCAACGTCCTCAAAGAAAAGGAGATCGCAACTGAGGACAAGC