VISDB Viral Integration Site DataBase

VIS ID

TVIS10016547

Fusion event

HBV-TAF15 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2008

Orient

+

Integrated sequence

CCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACTTG| |GCACAGACCTGGCCGTTGCCGGGCAACGGGGTAAAGGTTCAGGTATTGTTTACACAGAAAGGCCTTGTAAGTTGGCGAGAAAGTGAAAGCCTGCTTAGAT

Chromosome

chr17

Cytoband

q12

Reference genome

Start

End

34155943/35828939 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-181a-5p ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-501-5p ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-10a-5p ; hsa-mir-196a-5p

Nearest miRNA

hsa-mir-1180/Upstream/3478737; hsa-mir-10226/Downstream/1204806;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/19033, chr17-CpG: 21/Downstream/101703

Nearby gene

MMP28(-33303) ; HEATR9(+26016) ;

Nearest cancer related gene

TAF15(OG, No orient, 0)

Upstream sequence

TGAGGTTTGTAAGATCATCCTTAATTGGTATATAGGTATTTCACATAGTGTGGACTTGATCCACTTTACTTGAAATTTAGTTGTAAGAATTGATCAACCA

Downstream sequence

ctctagaaTGATAGATTCTTGGCCTCCTGAGATGTTGATAAATGCTGAATCCAGAAAGCCTTTTTACCATGCATGTAAGACATAGGAGGAAATAAAATGT