VISDB Viral Integration Site DataBase

VIS ID

TVIS10016548

Fusion event

HBV-MED13 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1476

Orient

+

Integrated sequence

TGGTGCGCAGACCAATTTATGCCTACAGCCTCCTAGTACAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTCTTTAAACAAACAGTCTTTG| |AAGTATGCCTCAAGGTCGGTCGTTGACATTGCTGAGAGTCCAAGAGTCCTCTTATGTAAGACCTTGGGCAATATTTGGTGGGCGTTCACGGTGGTCTCCA

Chromosome

chr17

Cytoband

q23.2

Reference genome

Start

End

60074185/61996824 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-208a-3p ; hsa-mir-151a-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-1303 ; hsa-mir-30c-5p ; hsa-mir-196a-5p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-5580-3p ; hsa-mir-8084 ; hsa-mir-6831-3p ; hsa-mir-205-5p ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-5585-3p ; hsa-mir-4708-5p ; hsa-mir-1253 ; hsa-mir-153-5p ; hsa-mir-95-5p ; hsa-mir-5197-3p ; hsa-mir-338-5p ; hsa-mir-5692a ; hsa-mir-3591-5p ; hsa-mir-4460 ; hsa-mir-4727-3p ; hsa-mir-4775 ; hsa-mir-7160-5p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-27b-5p ; hsa-mir-6718-5p ; hsa-mir-203b-5p ; hsa-mir-590-3p ; hsa-mir-562 ; hsa-mir-140-5p ; hsa-mir-568 ; hsa-mir-4477a ; hsa-mir-3163 ; hsa-mir-595 ; hsa-mir-224-5p ; hsa-mir-4783-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485

Nearest miRNA

hsa-mir-10226/Upstream/1953719; hsa-mir-1250/Downstream/947391;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/68769, chr17-CpG: 101/Downstream/68062

Nearby gene

INTS2(-68808) ; TBC1D3P2(+267881) ;

Upstream sequence

cccttcagcctagatgctttccgcaatcgtggagaggcggactgcaggaggctgtgctgacagcacgccagcagctggggcagcaagtccttcactgatg

Downstream sequence

gctccacaaggacaggggtctaacctttgttcactaatttagcacagatgcctagagtacctggtacataataggtgtcaatacttgctagtgaataaat