Basic Information
VIS ID
TVIS10016552
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
2650
Orient
+
Integrated sequence
TTTTCCGAAAGCCCAGGATGATGGGATGGGAATACAGGTGCAATTTCCGTCCGAAGGTTTGGTACAGCAACAGGAGGGATACATAGAGGTTCCTTGAGCA| |GTAGTCATGCAGGTCCGGCATGGTCCCGTGCTGGTTGTTGAGGATCCTGGAATTAGAGGACAAACGGGCAACATACCTTGATAGTCCAGAAGAACCAACA
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
114832630/114075053 (Hg38)
End
114832630/114075053 (Hg38)
Orient
+
Fragile sites / regions
FRA2S ; FRA2B
Nearest miRNA
hsa-mir-1285-2/Upstream/353685; hsa-mir-10b/Downstream/13348484;
Nearest TSS
ENST00000437798/Upstream/95144; ENST00000492708/Downstream/48240;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/94941, chr2-CpG: 51/Downstream/587098
Nearby gene
LINC01191(-67743) ; DPP10(+367268) ;
Upstream sequence
gaaaggttaagaactactCACCTTAACAAAGAGAAAAATCCAAGCCAAAAAAGAGCCCCACAGTCAATACGGAGAAGTGATGTCAGGAGCCAGATGAAAG
Downstream sequence
TAATCTCCCAGCATCCCTGAGCTAACTCTAGCACCTCTTCCAGCACTTTAAGAGGCCACAAACATAGTCTGCTTTTCAGACTCCCTTAAAAAAATGCCAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate