VISDB Viral Integration Site DataBase

VIS ID

TVIS10016553

Fusion event

HBV-JAG1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2199

Orient

+

Integrated sequence

TGCTTAGATTGAATACATGCATACAAAGGCATCAACGCAGGATAACCACATTGTGTAAAAGGGGCAGCAAAACCCAAAAGACCCACAATTCGTTGACATA| |CTTTCCAATCAATAGGCCTGTTAATAGGAAGTTTTCTAAAACATTCTTTGATTTTTTGTATGATGTGTTCTTGTGGCAAGGACCCATAACATCCAATGAC

Chromosome

chr20

Cytoband

p12.2

Reference genome

Start

End

10649215/10668567 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-21-5p ; hsa-mir-200c-3p ; hsa-mir-34b-3p ; hsa-mir-143-3p ; hsa-mir-145-5p ; hsa-mir-524-5p ; hsa-mir-375 ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-199b-5p ; hsa-mir-124-3p ; hsa-mir-214-3p ; hsa-mir-199a-5p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-192-3p ; hsa-mir-4480 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-5003-3p ; hsa-mir-4282 ; hsa-mir-137 ; hsa-mir-3613-3p ; hsa-mir-26a-5p ; hsa-mir-410-3p ; hsa-mir-26b-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/18872; hsa-mir-1-1/Downstream/7802048;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/234222, chr20-CpG: 255/Downstream/3358

Nearby gene

SLX4IP(-45188) ; BTBD3(+1222261) ;

Upstream sequence

GGAACAGCCAGCCAGCCACGCAACAGGCACATAACTCTTTCAGGGCTGGGGCATGTGCGGATGCTTTAAGTCAGCAGCTGTTTTTAGCTTTGCTATATAT

Downstream sequence

TCTACAATGGGGCCAGTGGGTGATATGAATCCAGCCAAGGCCTCTGGTTCACATTCCTGTTTTCAGATCAGGAACTGTGAAGGCTCCTTGTTACCTTGAC