Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016559
Fusion event
HBV-ASAP1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1782
End
1826
Orient
+
Integrated sequence
TCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATT
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
End
131217205/130204959 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-106b-5p ; hsa-mir-203a-3p ; hsa-mir-136-5p ; hsa-mir-544a ; hsa-mir-136-3p ; hsa-mir-432-5p ; hsa-mir-493-3p ; hsa-mir-208a-3p ; hsa-mir-208b-3p ; hsa-mir-27b-5p ; hsa-mir-3138 ; hsa-mir-3148 ; hsa-mir-4432 ; hsa-mir-4463 ; hsa-mir-4520-3p ; hsa-mir-4635 ; hsa-mir-4720-3p ; hsa-mir-499a-5p ; hsa-mir-6124 ; hsa-mir-6864-5p ; hsa-mir-8071 ; hsa-mir-8087 ; hsa-mir-875-3p
Nearest miRNA
hsa-mir-1204/Upstream/196445; hsa-mir-10400/Downstream/2841522;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/188049, chr8-CpG: 135/Downstream/152882
Upstream sequence
TTTCGACAGGACCATGTTCACTAAGTGAACTTGACTAATTGGTTCAGTGGACTCTAATCAATTTTAACGTGAATGTAGAAAACCTAATGGTATATTGGCT
Downstream sequence
cataaaaataaaaataatgaaaacttcacctgccttaaggctgtgagggtgagaccagctcttttatcaaagagatattgattagcaaaatgttagagac
Target sequence
agtcaccacAGTATAAAGACAAGCTCCTGTTatcagaattacttgtatagtaaaagttaac
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.