Basic Information
VIS ID
TVIS10016562
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1415
Orient
-
Integrated sequence
GCTTGAACAGTAGGACATGAACAAGAGATGATTAGGCAGAGGTGAAAAAGTTGCATGGTGCTGGTGCGCAGACCAATTTATGCCTACAGCCTCCTAGTAC| |AAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTCTTTAAACAAACAGTCTTTGAAGTATGCCTCAAGGTCGGTCGTTGACATTGCTGAGAGT
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
191893651/191924521 (Hg38)
End
191893651/191924521 (Hg38)
Orient
-
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/11486131; hsa-mir-1182/Downstream/791807;
Nearest TSS
ENST00000473358/Upstream/34292; ENST00000491030/Downstream/233936;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5243572, chr1-CpG: 56/Downstream/883981
Nearby gene
LINC01720(-1122863) ; RGS18(+233940) ;
Upstream sequence
tcattatgatgaggaatgggtgagtggtagttacagtagtgaaacaggtatgaagagttctgttttggcaatgtttgaggttattattgacatacttata
Downstream sequence
aatccatgaggcagaggtcgcagtgagccaggattgcaccattgcactccagctgggtgacagagtgagattctgtctcaaaaaaaaaaaaaaGGAGAGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate