Basic Information
VIS ID
TVIS10016563
Fusion event
HBV-chr10 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
270
Orient
+
Integrated sequence
AAACCCAGCCCGAATGCTCCAGCTCCTACCTTGTTGGCGTCTGGCCAGGTGTCCTTGTTGGGATTGAAGTCCCAATCTGGATTTGCGGTGTTTGCTCTGA| |AGGCTGGATCCAACTGGTGGTCGGGAAAGAATCCCAGAGGATTGCTGGTGGAAAGATTCTGCCCCATGCTGTAGATCTTGTTCCCAAGAATATGGTGACC
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
133233840/131435577 (Hg38)
End
133233840/131435577 (Hg38)
Orient
+
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/472909; hsa-mir-202/Downstream/1811934;
Nearest TSS
ENST00000439456/Upstream/123856; ENST00000634373/Downstream/354622;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/90998, chr10-CpG: 25/Downstream/84188
Nearby gene
TCERG1L(-123856) ; PPP2R2D(+514119) ;
Upstream sequence
AGGACAAACAAATCTTAGCATAGATCTCACTGTACTAGAGACAAAAGGGTTAGAATCAAGCAGACTTTTCCACAGCTAGCACTAGGGATGACAGTAAATG
Downstream sequence
ctttgtgtgcacagtgaagtttcagaatcagtgACTTGGGTAATAGATAGTATAGTTTCACTTCCAGTTCAAATGAACCCTTTCCTAAAATATTCTGTGT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate