VISDB Viral Integration Site DataBase

VIS ID

TVIS10016565

Fusion event

HBV-TMEM41B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1389

Orient

-

Integrated sequence

AAAGCCACCCAAGGCACAGCTTGGAGGCTTGAACAGTAGGACATGAACAAGAGATGATTAGGCAGAGGTGAAAAAGTTGCATGGTGCTGGTGCGCAGACC| |AATTTATGCCTACAGCCTCCTAGTACAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTCTTTAAACAAACAGTCTTTGAAGTATGCCTCAA

Chromosome

chr11

Cytoband

p15.4

Reference genome

Start

End

9302969/9281422 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-3940-3p ; hsa-mir-6771-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-3190-3p ; hsa-mir-4253 ; hsa-mir-6862-5p ; hsa-mir-3945 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6134 ; hsa-mir-4795-5p ; hsa-mir-1305 ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-549a ; hsa-mir-5003-3p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-24-3p ; hsa-mir-4755-3p ; hsa-mir-1238-5p ; hsa-mir-1270 ; hsa-mir-153-5p ; hsa-mir-3174 ; hsa-mir-3910 ; hsa-mir-4327 ; hsa-mir-4459 ; hsa-mir-4481 ; hsa-mir-455-3p ; hsa-mir-4633-3p ; hsa-mir-4683 ; hsa-mir-4745-5p ; hsa-mir-4758-5p ; hsa-mir-548an ; hsa-mir-620 ; hsa-mir-6499-3p ; hsa-mir-6500-5p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6826-5p ; hsa-mir-6840-3p ; hsa-mir-6874-5p ; hsa-mir-6880-5p ; hsa-mir-1288-5p ; hsa-mir-450a-1-3p ; hsa-mir-4768-3p ; hsa-mir-6888-5p ; hsa-mir-7112-5p

Nearest miRNA

hsa-mir-210/Upstream/191043; hsa-let-7a-2/Downstream/1226848;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/15878, chr11-CpG: 80/Downstream/32761

Nearby gene

DENND5A(-16098) ; TMEM41B(+13673) ;

Upstream sequence

cgacatttcccctaggtggtcagagcacagtttgattttatacattttcgggagacatgagacatcaatcaacatatgtaatatgaacattggttccatc

Downstream sequence

aggtcagctaggaatattgggatctcacggtatgatggtgagtcccctgggttttattttcctcatatattcaagatttggagctgaagaagcttgtaac