Basic Information
VIS ID
TVIS10016570
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1571
Orient
+
Integrated sequence
CTTTGAAGTATGCCTCAAGGTCGGTCGTTGACATTGCTGAGAGTCCAAGAGTCCTCTTATGTAAGACCTTGGGCAATATTTGGTGGGCGTTCACGGTGGT| |CTCCATGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCG
Host Sequence
Chromosome
chr12
Cytoband
q11
Reference genome
GRCh37/hg19
Start
38029560/37635758 (Hg38)
End
38029560/37635758 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1244-3/Upstream/11761679; hsa-let-7i/Downstream/4687942;
Nearest TSS
ENST00000382841/Upstream/3416905; ENST00000553138/Downstream/680820;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/3285079, chr12-CpG: 44/Downstream/502468
Nearby gene
ALG10(-3848324) ; ALG10B(+680996) ;
Upstream sequence
atggggtttgtgttaaatgatttggctcaggatcatgagagagtagtaccatgctgcatattgctagcccgggaaaagatcaagattcacaatttcaagg
Downstream sequence
aattccatcagtttttgcttcatatatatttatggtttgttattaggtacatatatgttcataatttttctatattcttgctatattgaaacatattaat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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