VISDB Viral Integration Site DataBase

VIS ID

TVIS10016571

Fusion event

HBV-EEA1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2214

Orient

-

Integrated sequence

CATGCATACAAAGGCATCAACGCAGGATAACCACATTGTGTAAAAGGGGCAGCAAAACCCAAAAGACCCACAATTCGTTGACATACTTTCCAATCAATAG| |GCCTGTTAATAGGAAGTTTTCTAAAACATTCTTTGATTTTTTGTATGATGTGTTCTTGTGGCAAGGACCCATAACATCCAATGACATAACCCATAAAATT

Chromosome

chr12

Cytoband

q22

Reference genome

Start

End

93231381/92837605 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-5682 ; hsa-mir-585-5p ; hsa-mir-3152-3p ; hsa-mir-6867-5p ; hsa-mir-3650 ; hsa-mir-509-3p ; hsa-mir-101-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p

Nearest miRNA

hsa-let-7i/Upstream/6092456; hsa-mir-1178/Downstream/1724184;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/691048, chr12-CpG: 133/Downstream/90961

Nearby gene

PLEKHG7(-65513) ; NUDT4(+540319) ;

Upstream sequence

GGGCTGGCATTTATATCgttatgggaaaccatcctaaaaatcctccacatgggattagaatccccatgacatcatcaagtaacaatttttctccttgtga

Downstream sequence

TCCCTATCTTGAttttttttttttttttttttttttgagagagtcttgctctgttgcccaggctggagtgcaatggtgcgatctcagctgtcagtgcaac