Basic Information
VIS ID
TVIS10016572
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1049
Orient
+
Integrated sequence
CTTCCAAAAGTGAGACAAGAAATGTGAAACCACAAGAGTTGCCTGAACTTTAGGCCCATATTAGTGTTGACATAACTGACTACTAGGTCTCTAGACGCTG| |GATCTTCCAAATTAACACCCACCCAGGTAGCTAGAGTCATTAGTTCCCCCCAGCAAAGAATTGCTTGCCTGAGTGCAGTATGGTGAGGTGAACAATGCTC
Host Sequence
Chromosome
chr13
Cytoband
q12.11
Reference genome
GRCh37/hg19
Start
22465784/21891645 (Hg38)
End
22465784/21891645 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-4499/Upstream/1457799; hsa-mir-1267/Downstream/2270771;
Nearest TSS
ENST00000623511/Upstream/13485; ENST00000611481/Downstream/149330;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/216029, chr13-CpG: 30/Downstream/804796
Nearby gene
FGF9(-187144) ; BASP1P1(+1005384) ;
Upstream sequence
ttgacttttccagaaatgtcatatggttgaaataatatagtatgcaggcttttcagaccactcctcttgcttggtaacatgcatttatggttcttctatg
Downstream sequence
tctattcatggcttggtagcttgtttctttttattgctgaataataaccagtgtgtggatgtacctcaatgtgtttattcatctcctgttgagggacacc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate