Fusion event
HBV-HTR2A integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CCCACAAAATGAGGCGCTATGTGTTGTTTCTCTCTTATATAATATACCCGCCTTCCATAGAGTGTGTAAATAGTGTCTAGTTTGGAAGTAATGATTAACT| |AGATGTTCTGGATAATAAGGTTTAATACCCTTATCCAATGGTAAATATTTGGTAACCTTTGGATAAAACCTGGCAGGCATAATCAATTGCAATCTTCTTT
End
47470747/46896612 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-2276/Upstream/2700412; hsa-mir-1267/Downstream/3099803;
Upstream sequence
TTTATCATTGTTTCTTTCTTCTTGAAGTCCTGTCTTCTCTTTTCTAGGTTTGGATGATATTATTTCCCCATTGTTAAGAGTTCCTAGAAAACGGCTTGTC
Downstream sequence
ATGGAAACCTTTTCCTGACTTTTCTGTCTCCCCCTAGTCTCACAGTGGGCCCCTCCATCACCCTTCCATCCTCGGGGCCTGCCAGTAGGATGAGGAGCAG
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.