VISDB Viral Integration Site DataBase

VIS ID

TVIS10016574

Fusion event

HBV-SHISA9 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2309

Orient

+

Integrated sequence

AATAGGCCTGTTAATAGGAAGTTTTCTAAAACATTCTTTGATTTTTTGTATGATGTGTTCTTGTGGCAAGGACCCATAACATCCAATGACATAACCCATA| |AAATTTAGAGAGTAACCCCATCTCTTTGTTTTGTTAGGGTTTAAATGTATACCCAAAGACAAAAGAAAATTGGTAACAGCGGTAAAAAGGGACTCAAGAT

Chromosome

chr16

Cytoband

p13.12

Reference genome

Start

End

13250153/13156296 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4531 ; hsa-mir-7847-3p ; hsa-mir-4764-5p ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-3605-5p ; hsa-mir-764 ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-1265 ; hsa-mir-3914 ; hsa-mir-5096 ; hsa-mir-7641 ; hsa-mir-197-3p ; hsa-mir-4695-3p ; hsa-mir-4716-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-1911-3p ; hsa-mir-4261 ; hsa-mir-873-5p ; hsa-mir-1285-5p ; hsa-mir-4496 ; hsa-mir-552-3p ; hsa-mir-5197-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-3187-3p ; hsa-mir-653-3p ; hsa-mir-4529-5p ; hsa-mir-6847-3p ; hsa-mir-539-5p ; hsa-mir-3190-5p ; hsa-mir-3919 ; hsa-mir-4756-3p ; hsa-mir-548o-3p ; hsa-mir-5680 ; hsa-mir-1323 ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-551b-5p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-7156-3p ; hsa-mir-6516-3p ; hsa-mir-1206 ; hsa-mir-1272 ; hsa-mir-3662 ; hsa-mir-8084 ; hsa-mir-642a-5p ; hsa-mir-6883-3p ; hsa-mir-6515-3p ; hsa-mir-6734-3p ; hsa-mir-877-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-454-5p ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-6505-5p ; hsa-mir-4789-5p ; hsa-mir-7153-3p ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-4474-5p ; hsa-mir-483-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-1225/Upstream/435925; hsa-mir-11401/Downstream/1147671;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/252463, chr16-CpG: 56/Downstream/763598

Nearby gene

SHISA9(-244646) ; ERCC4(+763860) ;

Upstream sequence

TCAATATATTTGCTTTGCAGTAAATATGTTCTTGCCCTCTATGCTTTATTGCCAATTAGGGCATAGGCCAACTTTATTTTTACTATTTGATTTTCATGCT

Downstream sequence

ggtacttgccagcatgcttagcactgagcctggcatgtagtaaactctaaatgagtgttagcccattattAATTGTGTGTACACGCGTATATGCACACAA