Basic Information
VIS ID
TVIS10016576
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1574
Orient
-
Integrated sequence
TGAAGTATGCCTCAAGGTCGGTCGTTGACATTGCTGAGAGTCCAAGAGTCCTCTTATGTAAGACCTTGGGCAATATTTGGTGGGCGTTCACGGTGGTCTC| |CATGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTC
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
51909154/51875243 (Hg38)
End
51909154/51875243 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/1132866; hsa-mir-11401/Downstream/4370277;
Nearest TSS
ENST00000527434/Upstream/103679; ENST00000568711/Downstream/203379;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/718894, chr16-CpG: 125/Downstream/670481
Nearby gene
SALL1(-723971) ; TOX3(+562763) ;
Upstream sequence
GAATAGGACCATGCCCGTCTTATCATTGTGTTCTCTGTGTCTTAATTTAAaaggaagaagaaaggaaaaaaagaagaaaggaaggaggagagagaaggaa
Downstream sequence
aaaggaatgaagaaaggaagAGGAGAACTAAAGAAAGAGCAAAATTAACTCAGAAGACGGAATTAATGGTTAAATCAGTGGTGGTCATACTATCgaccaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate