Basic Information
VIS ID
TVIS10016577
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
973
Orient
-
Integrated sequence
GGCATTTGGTGGTCTATAAGCTGGAGGAGTGCGAATCCACACTCCGAAAGACACCAAATACTCTATAACTGTTTCTCTTCCAAAAGTGAGACAAGAAATG| |TGAAACCACAAGAGTTGCCTGAACTTTAGGCCCATATTAGTGTTGACATAACTGACTACTAGGTCTCTAGACGCTGGATCTTCCAAATTAACACCCACCC
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2309247/2405953 (Hg38)
End
2309247/2405953 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-132/Upstream/355573; hsa-mir-10226/Downstream/286908;
Nearest TSS
ENST00000595228/Upstream/4835; ENST00000571289/Downstream/9896;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/3763, chr17-CpG: 26/Downstream/105814
Nearby gene
MNT(-4989) ; LOC284009(+1027) ;
Nearest cancer related gene
MNT(TSG, -4989) ;
Upstream sequence
TGGCTGACACTCACCCCTTACCCCAGTGCCTGGATCACTTTTCAAACATGGTGCTCTCACCAttttctttttcttttcttttcttttctttttctttttc
Downstream sequence
gcatttacatggtatgaggtatttgagtagcgcagagatgagttaaaggatacctgaggatgtgcataggttacatgtaagggatttgagcatcatccat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate