Basic Information
VIS ID
TVIS10016578
Fusion event
HBV-ASIC2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
3189
Orient
-
Integrated sequence
GAACAGGGTTTACTGTTCCTGAACTGGAGCCACCAGCAGGGAAATACAGGCCTCTCACTCTGGGATCTTGCAGAGTTTGGTGGAAGGTTGTGG| |
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
32027932/33700913 (Hg38)
End
32027932/33700913 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASIC2
Nearest miRNA
hsa-mir-1180/Upstream/1350711; hsa-mir-10226/Downstream/3332832;
Nearest TSS
ENST00000595228/Upstream/12110; ENST00000582685/Downstream/115848;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/407466, chr17-CpG: 46/Downstream/339011
Nearby gene
AA06(-167177) ; CCL2(+554363) ;
Upstream sequence
CTGGCCTGTGCCCCAGAAACCTACACTTTAGAAGGATAATGGCTCCCAAATGGCGTTTTTGTCTCTGCTAAGCCTCCAGGAAAGTGAGCATCAGTGAGTC
Downstream sequence
CAAATCTGACCTCCTAAAGCTGAAGTACAGAGTAGAATTGGGGGAGCATTCTAAGGCTTGCTGTAAAATTAATCACCACACAATAATAATTTTAAAAAGC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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