Basic Information
VIS ID
TVIS10016584
Fusion event
HBV-DZANK1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
315
End
373
Orient
-
Integrated sequence
TGGTGGAAAGATTCTGCCCCATGCTGTAGATCTTGTTCCCAAGAATATGGTGACCCACA
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
18419624/18438980 (Hg38)
End
18419644/18439000 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA20A
Target gene
DZANK1
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-103a-2/Upstream/7789285; hsa-mir-1-1/Downstream/31615;
Nearest TSS
ENST00000382410/Upstream/5215; ENST00000461589/Downstream/9988;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/150219, chr20-CpG: 65/Downstream/27785
Upstream sequence
GTcaagcactctactcttgtcccacctctgggcctgtgtctctacctggagcatgcatcctttccaccttcttctccccagctggctatgtccccctcat
Downstream sequence
aagattcaatccatagcatggacataacaacaaacccccaaaatacatgaagcaaaaactacaagtcagagttgaggTtaaggttccatctatcacctgc
Target sequence
cgaattttggccaagacaca
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate