Basic Information
VIS ID
TVIS10016585
Fusion event
HBV-chr22 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
2803
Orient
-
Integrated sequence
TAGAGGACAAACGGGCAACATACCTTGATAGTCCAGAAGAACCAACAAGAAGATGAGGCATAGCAGCAGGATGAAGAGGAAGATGATAAAACGCCGCAGA| |CACATCCAGCGATAACCAGGACAAGTTGGAGGACAAGAGGTTGGTGAGTGATTGGAGGTTGGGGACTGCGAATTTTGGCCAAGACACACGGTAGTTCCCC
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19672734/19685211 (Hg38)
End
19672734/19685211 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-3198-1/Upstream/1704250; hsa-let-7a-3/Downstream/278542;
Nearest TSS
ENST00000624155/Upstream/18188; ENST00000490204/Downstream/29253;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/28494, chr22-CpG: 103/Downstream/28780
Nearby gene
LINC00895(-118372) ; SEPTIN4(+29252) ;
Nearest cancer related gene
SEPTIN4(TSG, +29252) ;
Upstream sequence
atcaaatctttaaagaaaaatttatcaccactgttccagaaaataggtgaggaaagaagactttccaatttgttttatgcagctggaattacagtgatac
Downstream sequence
caaaaccagacaaagatagtagaaaaaaagaaaatctcagaaaaatatccctcatgaatatagaccaagaaaatatttaataaaatattagcaaatagaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate