MCCC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016587
Fusion event
HBV-MCCC1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
2758
Orient
-
Integrated sequence
GCAGGTCCGGCATGGTCCCGTGCTGGTTGTTGAGGATCCTGGAATTAGAGGACAAACGGGCAACATACCTTGATAGTCCAGAAGAACCAACAAGAAGATG| |AGGCATAGCAGCAGGATGAAGAGGAAGATGATAAAACGCCGCAGACACATCCAGCGATAACCAGGACAAGTTGGAGGACAAGAGGTTGGTGAGTGATTGG
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
182810141/183092353 (Hg38)
End
182810141/183092353 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
MCCC1
Nearest miRNA
hsa-let-7g/Upstream/6577202; hsa-mir-1224/Downstream/794447;
Nearest TSS
ENST00000440867/Upstream/54998; ENST00000477699/Downstream/2254;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/27565, chr3-CpG: 60/Downstream/6630
Nearby gene
DCUN1D1(-111815) ; LAMP3(+29861) ;
Upstream sequence
agaaccataaaaatcctgtaaggaaacgtgggtaataccattcaggacatagacatgggcaaaggcttcatgtctaaaacaccaaaagcaatggcaacaa
Downstream sequence
ACTGACACAGTAAACGAATAAACGTAAGACGTGGCTTCCAATTTTTAACACATACCATATCTACATGCATGGAATTTCTGTCAGCCTCACTATAAACCGC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate