VISDB Viral Integration Site DataBase

VIS ID

TVIS10016588

Fusion event

HBV-TBCK integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1362

Orient

-

Integrated sequence

CTTTATAAGGGTCGATGTCCATGCCCCAAAGCCACCCAAGGCACAGCTTGGAGGCTTGAACAGTAGGACATGAACAAGAGATGATTAGGCAGAGGTGAAA| |AAGTTGCATGGTGCTGGTGCGCAGACCAATTTATGCCTACAGCCTCCTAGTACAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTCTTTAA

Chromosome

chr4

Cytoband

q24

Reference genome

Start

End

106997742/106076585 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-337-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-6740-5p ; hsa-mir-6729-3p ; hsa-mir-6780b-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-6741-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-1284 ; hsa-mir-202-5p ; hsa-mir-4436b-5p ; hsa-mir-223-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-567 ; hsa-mir-574-5p ; hsa-mir-6867-5p

Nearest miRNA

hsa-mir-12113/Upstream/4746171; hsa-mir-1243/Downstream/3412113;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/179973, chr4-CpG: 61/Downstream/958813

Nearby gene

NPNT(-104914) ; AIMP1(+239024) ;

Upstream sequence

aaaaaattattatatactttaagcagataacaataaatatcacagacaagtaagaaaaaatgctatggaaacagagaagagaatcaagggagaatcaaag

Downstream sequence

gtgaaagaaaaaatcgtataggtaactagagagaagcggcgggtcacttacaaagggaactctgtcaggctcagtagacctttccgcagaaactttacaa