Basic Information
VIS ID
TVIS10016589
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1904
Orient
-
Integrated sequence
CAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGG| |AGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACA
Host Sequence
Chromosome
chr4
Cytoband
q33
Reference genome
GRCh37/hg19
Start
171361840/170440689 (Hg38)
End
171361840/170440689 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/5054352; hsa-mir-1305/Downstream/745495;
Nearest TSS
ENST00000502981/Upstream/97600; ENST00000505329/Downstream/303029;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/350337, chr4-CpG: 117/Downstream/1371894
Nearby gene
AADAT(-350468) ; HSP90AA6P(+140780) ;
Upstream sequence
ctgtgtacataagtgtattttgtaatggcttgtaatagtctttccttttcatatttagtgctctgttcaagatctattttaacgtgggtctggtggtaaa
Downstream sequence
ATGCTTATGTTGAAGAGCAAAAATCAACAGAGTGCAATTCTAAGGCAATTTAACTATGTTCCTTTATGGTGTCTTCAAACCTGCACTATATAGCAACTTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate