Basic Information
VIS ID
TVIS10016592
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
2970
Orient
-
Integrated sequence
GCGAATTTTGGCCAAGACACACGGTAGTTCCCCCTAGAAAATTGAGAGAAGTCCACCACGAGTCTAGACTCTGCGGTATTGTGAGGATTCTTGTCAACAA| |GAAAAACCCCGCCTGTAACACGAGAAGGGGTCCTAGGAATCCTGATGTGATGTTCTCCATGTTCAGCGCAGGGTCCCCAATCCTCGAGAAGATTGACGAT
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
118132717/118797022 (Hg38)
End
118132717/118797022 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/2541188; hsa-mir-103a-1/Downstream/177564;
Nearest TSS
ENST00000502646/Upstream/11563; ENST00000515335/Downstream/191198;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2220334, chr5-CpG: 69/Downstream/191130
Nearby gene
SEMA6A(-2222166) ; DTWD2(+39851) ;
Upstream sequence
GCGGAAAGCCGCCGGGTCCCCGCGCTGCACCAGCCGCCAGCCCTGGGGCCCCAGGCGCCGCACGAACGTGGCCAGCGGCAGCACCTCGCGGTAGTGGCTG
Downstream sequence
CCTAACAACCTTTACTATCTGCATCCCATATTGGTGCCCTTCTAGTAACTGAAATTATTTGGTGTCTTAGATTGTATCCCTGGACGGGCTAGAGTTAATA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate