VISDB Viral Integration Site DataBase

VIS ID

TVIS10016594

Fusion event

HBV-ZNF354C integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1978

Orient

-

Integrated sequence

TGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCA| |GCCAGTGGGGGTTGCGTCAGCAAACACTTGGCACAGACCTGGCCGTTGCCGGGCAACGGGGTAAAGGTTCAGGTATTGTTTACACAGAAAGGCCTTGTAA

Chromosome

chr5

Cytoband

q35.3

Reference genome

Start

End

178498276/179071275 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-1273e ; hsa-mir-636 ; hsa-mir-4645-3p ; hsa-mir-3973 ; hsa-mir-455-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-548l

Nearest miRNA

hsa-mir-10397/Upstream/2441775; hsa-mir-1229/Downstream/727003;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/10355, chr5-CpG: 117/Downstream/49145

Nearby gene

ZNF879(-36888) ; ADAMTS2(+39575) ;

Upstream sequence

CTAGCCCACGAGCTCAGGGTTGGTTGGTGGGCCCGTGGAAGGCTGGTGATTTGAGAGGAGAAGAAGGTCACGGATGCTGACGTTCCATCAGTTCACTGAT

Downstream sequence

ATGAGATGATTGATAAGATGTGTTTCAGGTCTGGAGTTCTAGTAGTCGGTCATTTTATCATTTCTTAATATTTAATGACTTTGCCAGGCTCAtttttttt