Basic Information
VIS ID
TVIS10016595
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
321
Orient
+
Integrated sequence
TCCTTGTTGGGATTGAAGTCCCAATCTGGATTTGCGGTGTTTGCTCTGAAGGCTGGATCCAACTGGTGGTCGGGAAAGAATCCCAGAGGATTGCTGGTGG| |AAAGATTCTGCCCCATGCTGTAGATCTTGTTCCCAAGAATATGGTGACCCACAAAATGAGGCGCTATGTGTTGTTTCTCTCTTATATAATATACCCGCCT
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
25139395/25139167 (Hg38)
End
25139395/25139167 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-3691/Upstream/6567287; hsa-mir-10398/Downstream/2008459;
Nearest TSS
ENST00000381078/Upstream/82094; ENST00000461945/Downstream/139911;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/227809, chr6-CpG: 36/Downstream/525
Nearby gene
CMAHP(-775) ; CARMIL1(+140260) ;
Upstream sequence
GATGACTGGGGAGGAAACACAGGTCAGCATGGGAACAGGGGTCACAGTGGACACAAGGGTGGGCTGTCTCTCCACCTCCTCACATTATGCTAACAGGGAC
Downstream sequence
AAATTATTCCAAAAATATGTTCTAAATGTATTTGACAGGAAGAAGCCATTCTAAATTTCATGACTTCTCTTTTGACTTTGTTCTTACGAGTACAGATATC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate