LRRCC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016597
Fusion event
HBV-LRRCC1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1381
Orient
-
Integrated sequence
CATGCCCCAAAGCCACCCAAGGCACAGCTTGGAGGCTTGAACAGTAGGACATGAACAAGAGATGATTAGGCAGAGGTGAAAAAGTTGCATGGTGCTGGTG| |CGCAGACCAATTTATGCCTACAGCCTCCTAGTACAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTCTTTAAACAAACAGTCTTTGAAGTA
Host Sequence
Chromosome
chr8
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
86053216/85140981 (Hg38)
End
86053216/85140981 (Hg38)
Orient
-
Location type
Intronic
Target gene
LRRCC1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-12123/Upstream/4899508; hsa-mir-10400/Downstream/6064504;
Nearest TSS
ENST00000518652/Upstream/32319; ENST00000521234/Downstream/36060;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/33352, chr8-CpG: 113/Downstream/35985
Nearby gene
RALYL(-219138) ; E2F5(+36402) ;
Upstream sequence
ccaggttcaagcaattctcctgcctcaacctcttgagtagctgagatgacagtcatgcaccaccatgcctggctaatttttgtgtttttagtagggatgg
Downstream sequence
cttgaacctgggagccagaggttgccttgagccatgatcatgccactgcactccagcctgagtgacacagccagaccctgtctcaaaaataaaataaaaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate