Basic Information
VIS ID
TVIS10016599
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
3064
Orient
+
Integrated sequence
CAACAAGAAAAACCCCGCCTGTAACACGAGAAGGGGTCCTAGGAATCCTGATGTGATGTTCTCCATGTTCAGCGCAGGGTCCCCAATCCTCGAGAAGATT| |GACGATAAGGGAGAGGCAGTAGTCAGAACAGGGTTTACTGTTCCTGAACTGGAGCCACCAGCAGGGAAATACAGGCCTCTCACTCTGGGATCTTGCAGAG
Host Sequence
Chromosome
chr8
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
111042814/110030585 (Hg38)
End
111042814/110030585 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-12123/Upstream/5546120; hsa-mir-10400/Downstream/2612908;
Nearest TSS
ENST00000518652/Upstream/54738; ENST00000523264/Downstream/319022;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/54742, chr8-CpG: 21/Downstream/3402012
Nearby gene
KCNV1(-55855) ; CSMD3(+2192344) ;
Upstream sequence
gctcactgcaacctctgcttcctgggttaaagtgattctcctgcctcagcctcctgagtagctgggattacaggtgcatgccagtactcctggctaattt
Downstream sequence
gaggtgtgttctcaatACTCATAATCCATTTTTAATTTTGGATTTCATTTTTTTTGTTCTGATATAATTCTTGAGGCAATACACCATTTCATAAGTGAAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate