VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10016619

Fusion event

HBV-MACF1 integration

Validated

Yes

Detection method

invPCR+NAH

Data source

Curated

Sample type

Tumor

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2008

PubMed ID

18023912

Virus Sequence

Virus name

HBV

Reference genome

Not given

Region type

HBV-X

Host Sequence

Chromosome

chr1

Cytoband

p32

Reference genome

Not given

Start

9911738

End

(Hg38)

Location type

Intronic

Target gene

MACF1

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-16-5p ; hsa-mir-296-3p ; hsa-mir-615-3p ; hsa-mir-125a-5p ; hsa-mir-222-3p ; hsa-mir-30d-5p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p

Nearest CpG islands

None/Target, None/Upstream, None/Downstream

Reference

Toyoda, H., et al. Impact of hepatitis B virus (HBV) X gene integration in liver tissue on hepatocellular carcinoma development in serologically HBV-negative chronic hepatitis C patients.J Hepatol,2008, 48(1): 43-50.