VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10016676

Fusion event

HBV-SCARB1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Tumor

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

23842217

Virus Sequence

Virus name

HBV

Reference genome

Not given

Start

1769

Host Sequence

Chromosome

chr12

Cytoband

q24.3

Reference genome

Not given

Start

2710365

End

(Hg38)

Location type

intron

Target gene

SCARB1

miRNAs that regulate target gene

hsa-mir-185-5p ; hsa-mir-96-5p ; hsa-mir-223-3p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-324-5p ; hsa-mir-92a-3p ; hsa-mir-450b-5p ; hsa-mir-106a-3p ; hsa-mir-5739 ; hsa-mir-5091 ; hsa-mir-3121-5p ; hsa-mir-501-5p ; hsa-mir-3610

Nearest CpG islands

None/Target, None/Upstream, None/Downstream

Reference

Toyoda, H., et al. Impact of hepatitis B virus integration into liver tissue on the efficacy of peginterferon and ribavirin therapy in hepatitis B virus-negative chronic hepatitis C patients. J Clin Gastroenterol,2014, 48(1): 73-79.