VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10016691

Fusion event

HBV-POU6F1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Tumor

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

23842217

Virus Sequence

Virus name

HBV

Reference genome

Not given

Start

1510

Host Sequence

Chromosome

chr12

Cytoband

p13

Reference genome

Not given

Start

13727603

End

(Hg38)

Location type

intron

Target gene

POU6F1

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6758-3p ; hsa-mir-4279 ; hsa-mir-7111-3p ; hsa-mir-2355-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6756-3p ; hsa-mir-3127-3p

Nearest CpG islands

None/Target, None/Upstream, None/Downstream

Reference

Toyoda, H., et al. Impact of hepatitis B virus integration into liver tissue on the efficacy of peginterferon and ribavirin therapy in hepatitis B virus-negative chronic hepatitis C patients. J Clin Gastroenterol,2014, 48(1): 73-79.