Basic Information
VIS ID
TVIS10016927
Fusion event
HBV-LOC105369617 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
956
End
1046
Integrated sequence
CTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATC
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
5381317/5272151 (Hg38)
End
5381384/5272218 (Hg38)
Location type
Intronic
Target gene
LOC105369617
Nearest miRNA
hsa-mir-3649/Upstream/3611771; hsa-let-7i/Downstream/1691481;
Nearest TSS
ENST00000382841/Upstream/29000; ENST00000544842/Downstream/18262;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/128747, chr12-CpG: 56/Downstream/158511
Upstream sequence
gactctgtgagttgaaagcacacatcacaaagaagtatctgagaatgcttctgtccactttttatttgaagatatttcattttacaacataggcctcaga
Downstream sequence
CGCCCTGAGGAATGAGTGGTATGACTCTGAGGCTGTTCATGGGGAAATTGAGGTTTGGAGGGTTTAGGCAATGTAAACAATTGGCCCCAGCGGGATATGG
Target sequence
AAGGTCAGGGCAGCAATACCTTCCCATGACTGTCACTTATTTACAAACTCATCCATATCCTTCTAAC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate