hsa-mir-130b-3p _LIHC.png
SLMAP _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016928
Fusion event
HBV-SLMAP integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1839
End
1928
Integrated sequence
ATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
57897477/57911750 (Hg38)
End
57897562/57911835 (Hg38)
Location type
Intron
Target gene
SLMAP
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-21-5p ; hsa-mir-19b-3p
Nearest miRNA
hsa-let-7g/Upstream/2059156; hsa-mir-12124/Downstream/2705970;
Nearest TSS
ENST00000440867/Upstream/15409; ENST00000476471/Downstream/460;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/154487, chr3-CpG: 90/Downstream/96276
Upstream sequence
CAGACCCTGGAGTGCCGGAGCACAGCTCCCCAACTGGAGGTTGCCTCACGCCCCTTACATCTGGGGAGGGCCTGGCTGGGGCAGGTGCTGGAGCAAATCT
Downstream sequence
aacagaaaAACGAATCAAGGGCGTCAACTGTTTATTGCTTTTATTGCTTACCATTTGACCAAGCAATTCTACACATAGGATTCACCCTaaaaaaaaaaaa
Target sequence
aagcagagtaaagagccagagaatgacagtgagctgtttttcacatgagtcatcagaaaaggcctctttaaagaattgacatttg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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