Basic Information
VIS ID
TVIS10016937
Fusion event
HBV-LOC105373696 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
487
End
576
Integrated sequence
CAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCA
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
155885023/155028511 (Hg38)
End
155885094/155028582 (Hg38)
Location type
Intronic
Target gene
LOC105373696
Nearest miRNA
hsa-mir-128-1/Upstream/3660100; hsa-mir-10b/Downstream/4158253;
Nearest TSS
ENST00000437798/Upstream/60508; ENST00000416888/Downstream/995994;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/328954, chr2-CpG: 82/Downstream/1291157
Upstream sequence
cagacatttctccaaagagcatatactaaaggccaataagtacatgaTACCATTTCATATCCACCAGGAttggtgaggatgtagagaaactggaactctc
Downstream sequence
cttcattttctttgtcttcatctcattcatgaaatttgttttcattagatataaaaatctggattggttttttttttttaaaacactttactaatatcat
Target sequence
acaaagctttctgtagcaattaaagcacatctgctgacaaaaaaaaacaaaacaaaacaaacaaaaaaccc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate