Basic Information
VIS ID
TVIS10016948
Fusion event
HBV-chr5 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
967
End
1049
Integrated sequence
CAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTG
Host Sequence
Chromosome
chr5
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
81768360/82472541 (Hg38)
End
81768412/82472593 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/9593878; hsa-mir-103a-1/Downstream/367562;
Nearest TSS
ENST00000502646/Upstream/89596; ENST00000509506/Downstream/73717;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/194065, chr5-CpG: 23/Downstream/604690
Upstream sequence
TGTCCACACTCGCGCCCTGATTCTACATCAGGTTTCTACTGGCAGATGGCAACCCCACTGGGACCTGAAGCCTGCAGCCTCCCAGCTGCCCCTGCAGTGG
Downstream sequence
tattatatgttatatataatatataatatattatatataatatattatatattatatataatatataatatattataatatataatatataatatattat
Target sequence
gatatataatatataatatattatatattataatatattatatattataata
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate