BBS7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016954
Fusion event
HBV-BBS7 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
614
End
703
Integrated sequence
ATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTT
Host Sequence
Chromosome
chr4
Cytoband
q27
Reference genome
GRCh37/hg19
Start
122752481/121831326 (Hg38)
End
122752575/121831420 (Hg38)
Location type
Intron
Target gene
BBS7
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-12113/Upstream/7174472; hsa-mir-1305/Downstream/3675839;
Nearest TSS
ENST00000502981/Upstream/2653; ENST00000567769/Downstream/27603;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/7214, chr4-CpG: 50/Downstream/38625
Upstream sequence
AATTTACCATGTTATCTAATATTTTAACTTAATTGAATGAATAAACTCCCTATGCATCTGGACACATGCATGGAAAATTCACAAACATTTCAAACCAAAA
Downstream sequence
aggagtttgagaccagcttgggcaacacagtgagactctcttaaaaaaaaaaaagtagctattaagttggaccttaaaggataaacagTTTTGAATCTTA
Target sequence
aaggcttcaaaaatgtagctactgcaggatgcagtagcttgcacctataatcccagctactggggaggctgaggcaggaggattgcttgaagcc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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