Basic Information
VIS ID
TVIS10016955
Fusion event
HBV-chr10 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1825
End
1910
Integrated sequence
TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42387000/41853134 (Hg38)
End
42387074/41853208 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/6211882; hsa-mir-107/Downstream/1144355;
Nearest TSS
ENST00000439456/Upstream/3399953; ENST00000442306/Downstream/332131;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2910028, chr10-CpG: 184/Downstream/257825
Upstream sequence
gggctcaagtgattcccttgcctcggcctctggagtagctgggattataagcatgcaccaccacacctgCCTGTCTTTTAAGTTCACCATTCAGTTATTC
Downstream sequence
aatcaagtgtaatcatcatcaaatggaatcaaaaataaccatcatcagttggtattgaatggaattgtcatcaaatggaattcaaaggaatcatcatcaa
Target sequence
ctcgaatggaatcatcattgaatggaatcgaatggaatcatcgagtggaatcgaatagaatcatgatcaaatgg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate