VISDB Viral Integration Site DataBase

VIS ID

TVIS10016960

Fusion event

HBV-AGO2 integration

Validated

No

Detection method

Capture-NGS platform

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2019

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Start

1229

End

1319

Integrated sequence

CAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAA

Chromosome

chr8

Cytoband

q24.3

Reference genome

Start

End

141543818/140533719 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-376a-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-107 ; hsa-mir-99a-5p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-671-5p ; hsa-mir-652-3p ; hsa-mir-186-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3120-3p ; hsa-mir-3133 ; hsa-mir-184 ; hsa-mir-4795-3p ; hsa-mir-223-5p ; hsa-mir-5193 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-5002-5p ; hsa-mir-125a-3p ; hsa-mir-126-5p ; hsa-mir-548l ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548w ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548bb-5p ; hsa-mir-548c-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-6887-5p ; hsa-mir-548a-5p ; hsa-mir-6795-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-8085 ; hsa-mir-4723-5p ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4524a-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-6751-5p ; hsa-mir-6803-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-6811-5p ; hsa-mir-1275 ; hsa-mir-6511b-5p ; hsa-mir-6793-5p ; hsa-mir-92a-1-5p ; hsa-mir-6769b-5p ; hsa-mir-92a-2-5p ; hsa-mir-6769a-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-6878-5p ; hsa-mir-625-5p ; hsa-mir-1193 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-6841-3p ; hsa-mir-873-5p ; hsa-mir-6895-5p ; hsa-mir-583 ; hsa-mir-6825-5p ; hsa-mir-3144-5p ; hsa-mir-6781-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3649 ; hsa-mir-6797-5p ; hsa-mir-6077 ; hsa-mir-1249-5p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3918 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-6165 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-3175 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-8055 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-4785 ; hsa-mir-6755-3p ; hsa-mir-3613-3p ; hsa-mir-5094 ; hsa-mir-944 ; hsa-mir-548c-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-148a-3p ; hsa-mir-374b-3p ; hsa-mir-4766-3p ; hsa-mir-6792-5p ; hsa-mir-4522 ; hsa-mir-646 ; hsa-mir-548p ; hsa-mir-3664-5p ; hsa-mir-590-5p ; hsa-mir-4799-5p ; hsa-mir-506-5p ; hsa-mir-6074 ; hsa-mir-892c-5p ; hsa-mir-103a-3p ; hsa-mir-491-3p ; hsa-mir-4509 ; hsa-mir-4699-3p ; hsa-mir-3680-3p ; hsa-mir-302c-5p ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-802 ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-3121-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-4744 ; hsa-mir-548e-5p ; hsa-mir-4666a-5p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-95-5p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-4495 ; hsa-mir-5582-5p ; hsa-mir-4719 ; hsa-mir-4803 ; hsa-mir-5692a ; hsa-mir-548an ; hsa-mir-382-3p ; hsa-mir-124-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-6852-5p ; hsa-mir-6742-3p ; hsa-mir-939-3p ; hsa-mir-8064 ; hsa-mir-1911-5p ; hsa-mir-4682 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-6777-3p ; hsa-mir-4714-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-513b-5p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-145-3p ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-31-3p ; hsa-mir-6832-3p ; hsa-mir-4328 ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-578 ; hsa-mir-132-3p ; hsa-mir-1207-5p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-1298-3p ; hsa-mir-204-3p ; hsa-mir-3192-5p ; hsa-mir-3197 ; hsa-mir-3616-3p ; hsa-mir-3691-3p ; hsa-mir-3910 ; hsa-mir-4270 ; hsa-mir-4314 ; hsa-mir-4441 ; hsa-mir-4646-5p ; hsa-mir-4668-3p ; hsa-mir-4763-3p ; hsa-mir-510-3p ; hsa-mir-5187-5p ; hsa-mir-542-5p ; hsa-mir-602 ; hsa-mir-605-3p ; hsa-mir-6087 ; hsa-mir-6125 ; hsa-mir-619-5p ; hsa-mir-6506-5p ; hsa-mir-658 ; hsa-mir-6754-5p ; hsa-mir-6765-5p ; hsa-mir-6804-5p ; hsa-mir-6820-5p ; hsa-mir-8063 ; hsa-mir-92b-5p ; hsa-mir-10b-3p ; hsa-mir-181b-2-3p ; hsa-mir-181b-3p ; hsa-mir-2115-5p ; hsa-mir-2277-3p ; hsa-mir-34c-3p ; hsa-mir-3619-3p ; hsa-mir-3620-3p ; hsa-mir-3660 ; hsa-mir-3690 ; hsa-mir-4256 ; hsa-mir-4308 ; hsa-mir-4420 ; hsa-mir-4526 ; hsa-mir-4690-3p ; hsa-mir-4755-5p ; hsa-mir-4776-5p ; hsa-mir-5006-3p ; hsa-mir-504-5p ; hsa-mir-516a-3p ; hsa-mir-516b-3p ; hsa-mir-520a-3p ; hsa-mir-5685 ; hsa-mir-623 ; hsa-mir-6719-3p ; hsa-mir-6730-3p ; hsa-mir-6856-3p ; hsa-mir-7162-5p

Nearest miRNA

hsa-mir-1204/Upstream/5728676; hsa-mir-10400/Downstream/198845;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/21260, chr8-CpG: 18/Downstream/1703

Upstream sequence

caAgggaaatcacagaattttgtgttgtcatcaaaaatttgaaaaaagcagggtggaggtgagtcttatcacatctccatttaacttgcctgtctgattc

Downstream sequence

tcgctggaacccgggaggcagaggctgcagtgagctgagtacacgccactgcactccagcctgggcgacagagtgagactccgtctaaaaaaaaaaaaca

Target sequence

catggcaaaacaccatctctactaaaagtacaaaaattagccatgtgtggttgcgtacgcctgtaatcccagctacccaggaggctgaggcatgagaa