Basic Information
VIS ID
TVIS10016968
Fusion event
HBV-chr9 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
751
End
841
Integrated sequence
GGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCT
Host Sequence
Chromosome
chr9
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
44331538/42639482 (Hg38)
End
44331636/42639580 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/1405647; hsa-let-7a-1/Downstream/28170395;
Nearest TSS
ENST00000422679/Upstream/52948; ENST00000439824/Downstream/68220;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/70259, chr9-CpG: 30/Downstream/104009
Nearby gene
FGF7P5(-9843) ;
Upstream sequence
CCGCCGGACCTCTACCTCTAACTCACAAAGAAAGCCCATTTCCCTGTTGGCTGCAAAACTCCCCCAAGAAGCAAGTGCTTGCTCCTCGCAGCAGTAACTG
Downstream sequence
ataagtctgttgttaatctaatttacttcataggtaatttggccctttctttgagctgcctttaatatattttcttttgcattgaccacggctattctaa
Target sequence
tgtctccaaaaaaaagaaattattggatggcattttttttttctttaagaaggctaacgctaggccccaatcttttctaggttgcagggtttctgctg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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