Basic Information
VIS ID
TVIS10016969
Fusion event
HBV-chr13 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
249
End
313
Integrated sequence
CTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTC
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
54873691/54299556 (Hg38)
End
54873763/54299628 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-15a/Upstream/1489416; hsa-mir-1267/Downstream/12344;
Nearest TSS
ENST00000623511/Upstream/166690; ENST00000616396/Downstream/641215;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1097346, chr13-CpG: 25/Downstream/2841209
Upstream sequence
tttaggggtacaggtgtagttttgatacatgaatacagtgcatagtggtgaagtctgggcttttagtacaaccattacctgaatagtgtacattgtacct
Downstream sequence
tccttttccactcaaggttatgactaataggtgacaacttactactgccattttgttgcttgtttcctagttgttttgtaactcttgtcttttttttttt
Target sequence
tgtaggcagcacatagttgggtctttaaaaaatacattgagtcattctatgtctcttaattagatattttag
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate