CTNNA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016978
Fusion event
HBV-CTNNA2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
861
End
951
Integrated sequence
GTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAG
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
80278708/80051582 (Hg38)
End
80278807/80051681 (Hg38)
Location type
Intron
Fragile sites / regions
FRA2S
Target gene
CTNNA2
Nearest miRNA
hsa-mir-1285-2/Upstream/184999; hsa-mir-10b/Downstream/5731919;
Nearest TSS
ENST00000437798/Upstream/21031; ENST00000493024/Downstream/252593;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/538465, chr2-CpG: 101/Downstream/250871
Nearest cancer related gene
CTNNA2(TSG, No orient, 0)
Upstream sequence
attccattccgttccatttcattccattccattccattccagtccattgcattctattccagctgattccattccattccatgccattccattcgtgttg
Downstream sequence
AAAGGAACTCTTTTTCCCCCCCACAGAGGCCATTGCTCATGCCATTTTCTTGCCCTGAAGAATTCCTGAGGAAAATGAAAAGACAATGGCTGCATTTCAA
Target sequence
AATAACAGGCTGGATCCCAAAATCAATTTGAAAAACAGCAACAATGAAAAATCAGGGCTAGTTTAGATAATGAAGCAGTGAAGGGAGTTGATAGGAAGA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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