CTNNA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016979
Fusion event
HBV-CTNNA2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1714
End
1803
Integrated sequence
GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
80278606/80051480 (Hg38)
End
80278705/80051579 (Hg38)
Location type
Intron
Fragile sites / regions
FRA2S
Target gene
CTNNA2
Nearest miRNA
hsa-mir-1285-2/Upstream/184897; hsa-mir-10b/Downstream/5732021;
Nearest TSS
ENST00000437798/Upstream/20929; ENST00000493024/Downstream/252695;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/538363, chr2-CpG: 101/Downstream/250973
Nearest cancer related gene
CTNNA2(TSG, No orient, 0)
Upstream sequence
TTTTTACTTTTTAGCTTGAGATGTTTTTAACTGCATTTTTTTCTCTTAAGGAAGTTTTGATAAATGTAAAATTTCTTGTCTACTGCCATATTATCACTTT
Downstream sequence
GGGAATAACAGGCTGGATCCCAAAATCAATTTGAAAAACAGCAACAATGAAAAATCAGGGCTAGTTTAGATAATGAAGCAGTGAAGGGAGTTGATAGGAA
Target sequence
TTTATCCTTTAGAAAAGTGAATAATAATTTTTGCTGCAAAGTGGTATACCAGCACATTTGTCTATAAATTTACATTCTTGGATATTAGCAAAATTGCAA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate