VISDB Viral Integration Site DataBase

VIS ID

TVIS10016994

Fusion event

HBV-PGM2L1 integration

Validated

No

Detection method

Capture-NGS platform

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2019

PubMed ID

Virus name

HBV

Subtype

B

Reference genome

Start

1823

End

1904

Integrated sequence

TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG

Chromosome

chr11

Cytoband

q13.4

Reference genome

Start

End

74113888/74402843 (Hg38)

Location type

Promoter

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-93-5p ; hsa-mir-615-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6778-5p ; hsa-mir-6832-5p ; hsa-mir-1233-5p ; hsa-mir-4451 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6124 ; hsa-mir-3135a ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6856-5p ; hsa-mir-4496 ; hsa-mir-6758-5p ; hsa-mir-3910 ; hsa-mir-4796-3p ; hsa-mir-548an ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-4500 ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-mir-98-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-323a-3p ; hsa-mir-100-3p ; hsa-mir-606 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-2114-3p ; hsa-mir-6878-3p ; hsa-mir-496 ; hsa-mir-5681b ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-133a-5p ; hsa-mir-6778-3p ; hsa-mir-4774-5p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-1976 ; hsa-mir-150-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-186-3p ; hsa-mir-6504-3p ; hsa-mir-518e-3p ; hsa-mir-518f-3p ; hsa-mir-518d-3p ; hsa-mir-518c-3p ; hsa-mir-518b ; hsa-mir-518a-3p ; hsa-mir-3664-5p ; hsa-mir-4743-3p ; hsa-mir-4531 ; hsa-mir-6888-3p ; hsa-mir-642a-5p ; hsa-mir-6740-3p ; hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-3120-5p ; hsa-mir-29b-1-5p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-183-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p

Nearest miRNA

hsa-mir-10392/Upstream/3461; hsa-let-7a-2/Downstream/317425;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/3902, chr11-CpG: 50/Downstream/64287

Upstream sequence

gtgtgtggctgtgtatgttatctctgtgtctttgtgcctctgtgtgagctgtctgtaaatttgtgtgtgtgtatctgtgtctgtgttgtctgtgtgtgtg

Downstream sequence

ataatatatatatatGGGTATTGTTTGTACTATTTTTATTTTTGTAACTTTGACATCAtttttttcttttctttctttctttttttttgagactgggtcc

Target sequence

tgtatatattatatatattatgtatatataatatatattatgtatatat